Product

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID

CAS No.：17407-55-5

Other grades of this product :

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Basic information

Product Name:	(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID
Synonyms:	(S)-(+)-2-HYDROXY-3-METHYLBUTANOIC ACID;(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID;(S)-2-HYDROXY-3-METHYLBUTYRIC ACID;L-ALPHA-HYDROXYISOVALERIC ACID;2S-HYDROXY-3-METHYL-BUTANOIC ACID;2-HYDROXY-3-METHYLBUTYRIC ACID;3-METHYL-2-HYDROXY-BUTANOIC ACID;(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID, 99% (99% EE/GLC)
CAS:	17407-55-5
MF:	C5H10O3
MW:	118.13
EINECS:	605-704-7
Product Categories:	pharmacetical;Aliphatics;Carboxylic Acids;chiral;Carboxylic Acids
Mol File:	17407-55-5.mol

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Chemical Properties

Melting point	68-70 °C (lit.)
Boiling point	124-125 °C/13 mmHg (lit.)
density	1.136
refractive index	1.4641 (estimate)
Fp	112℃
storage temp.	Sealed in dry,Room Temperature
form	Powder
pka	3.87±0.16(Predicted)
color	White
optical activity	[α]20/D +19°, c = 1 in chloroform
BRN	1721140
CAS DataBase Reference	17407-55-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	3-10
Hazard Note	Irritant
HS Code	29181990

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Usage And Synthesis

Chemical Properties	white fine crystalline powder
Uses	A useful chiral building block for peptide synthesis. Used in the preparation of the cytotoxic didemnin cyclopeptides and of the antineoplastic agent dolastatin 15.

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Preparation Products And Raw materials

Raw materials

Sulfuric acid-->Sodium nitrite-->Ammonium sulfate-->L-Valine

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