Isoprocarb

CAS No.：2631-40-5

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Isoprocarb Basic information

Product Name:	Isoprocarb
Synonyms:	2-(1-Methylethyl)phenol 1-(N-MethylcarbaMate);NSC 191479;Isoprocarb 0.1;2-(1-Methylethyl)-phenol methyl-carbamate;2-(1-methylethyl)-phenomethylcarbamate;2-(1-Methylethyl)phenylmetylcarbamate;Isoprocarb-D3;2-Isopropylphenyl methylcarbamate
CAS:	2631-40-5
MF:	C11H15NO2
MW:	193.24
EINECS:	220-114-6
Product Categories:	INSECTICIDE
Mol File:	2631-40-5.mol

Isoprocarb Chemical Properties

Melting point	92.4°C
Boiling point	329.46°C (rough estimate)
density	1.0945 (rough estimate)
refractive index	1.5080 (estimate)
Fp	-18 °C
storage temp.	Sealed in dry,2-8°C
form	Crystalline
pka	12.22±0.46(Predicted)
BRN	1875020
CAS DataBase Reference	2631-40-5(CAS DataBase Reference)
NIST Chemistry Reference	2-(1-Methylethyl)phenyl methylcarbamate(2631-40-5)
EPA Substance Registry System	Isoprocarb (2631-40-5)

Safety Information

Hazard Codes	Xn,N,F
Risk Statements	22-50/53-67-65-38-11-20
Safety Statements	60-61-62-33-16-9-25
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	FB7880000
HS Code	29224999

MSDS Information

Isoprocarb Usage And Synthesis

Description	Isoprocarb, o-cumenyl methylcarbamate (IUPAC), consists of colorless crystals, which are sparingly soluble in water and are readily soluble in acetone and methanol. Isoprocarb is produced by reaction of 2-isopropylphenol with methylisocyanate. Isoprocarb is used for control of rice, cacao, sugarcane, and vegetable pests.
Chemical Properties	Isoprocarb is a carbamate insecticide. It is a colourless crystalline substance, sparingly soluble in water (0.265g/l) and readily soluble in acetone(400g/l) and methanol (125g/l). It is hydrolysed in alkaline media.The insecticide,with contact and stomach action, effectively controls leafhoppers,plant hoppers and aphids on a variety of crops like rice, cocoa, sugarcane and vegetables. Its residual activity gives effective pest control. It acts by inhibiting cholinesterase.
Uses	Isoprocarb is a non-systematic carbamate insecticide. Isoprocarb functions by reversibly inactivating the enzyme acetylcholinesterase in insects.
Safety Profile	Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by skin contact. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES. Used for controlling leafhoppers, planthoppers, and bugs in rice and cacao.
Toxicology	The insecticide isoprocarb is a Class II toxin (moderately hazardous), with the acute oral LD50 among rats being 403-485mg/kg, while the percutaneous LD50 among male rats and mice is>500mg. It is a PAN Bad Actor chemical, since it is a cholinesterase inhibitor. Symptoms of poisoning with this insecticide include muscle weakness,dizziness,salivation,nausea,vomiting,sweating,headache,effects on the CNS and depression. PPE such as splash-resistant safety goggles and chemicalresistant clothing, gloves and masks are advised.

Isoprocarb Preparation Products And Raw materials

Raw materials	Triethylamine-->Carbon tetrachloride-->Methylamine-->CARBON MONOXIDE-->PHOSGENE-->Carbaryl-->Propionitrile-->METOLCARB-->METHYL ISOCYANATE-->(+)-MENTHYL CHLOROFORMATE-->2-Isopropylphenol-->Propoxur-->N-METHYLURETHANE-->METHYLISOCYANATE 1 X 500MG NEAT
Preparation Products	Buprofezin+Isoprocarb,W.P.

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