(2-Bromoethoxy)-Tert-Butyldimethylsilane

CAS No.：86864-60-0

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE Basic information

Product Name:	(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE
Synonyms:	2-(tert-Butyldimethylsilyloxy)-1-bromoethane;2-(tert-Butyldimethylsilyloxy)bromoethane;2-(tert-Butyldimethylsilyloxy)ethyl bromide;2-Bromoethyl tert-butyldimethylsilyl ether;2-Bromoethyloxy(tert-butyl)dimethylsilane;(1-(2-BroMoethoxy)-2-Methylpropan-2-yl)diMethylsilane;Silane,(2-broMoethoxy)(1,1-diMethylethyl)diMethyl-;(2-BroMoethoxy)-tert-butyldiMethylsilane 99%
CAS:	86864-60-0
MF:	C8H19BrOSi
MW:	239.23
EINECS:
Product Categories:	Miscellaneous;Organic Building Blocks;Oxygen Compounds;Protected Alcohols/Phenols
Mol File:	86864-60-0.mol

(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE Chemical Properties

Boiling point	70-75 °C2.5 mm Hg(lit.)
density	1.115 g/mL at 25 °C(lit.)
refractive index	n20/D1.444(lit.)
Fp	163 °F
storage temp.	2-8°C
form	Liquid
Specific Gravity	1.115
color	White to pale yellow
Hydrolytic Sensitivity	7: reacts slowly with moisture/water

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
HS Code	29319090

MSDS Information

Provider	Language
SigmaAldrich	English

(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE Usage And Synthesis

Chemical Properties	colorless liquid
Uses	(2-Bromoethoxy)-tert-butyldimethylsilane was used in the synthesis of 4-(3-hydroxypropyl)-4′-methyl-2,2′-bipyridine.It may be used as a reagent for the selective N-alkylation of 5-piperazin-1-yl-1H-indole and (1H-indol-2-yl)-piperazin-1-yl-methanone and also in the synthesis of 2-[3-[(3,4,5-trimethoxyphenyl)thio]-1H-indol-5-yloxy]ethanol.
Uses	(2-Bromoethoxy)-tert-butyldimethylsilane can be used in N-alkylation with 5-piperazin-1-yl-1H-indole to synthesize 5-(4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperazin-1-yl)-1H-indole.
General Description	(2-Bromoethoxy)-tert-butyldimethylsilane is a silane derivative.

(2-BROMOETHOXY)-TERT-BUTYLDIMETHYLSILANE Preparation Products And Raw materials

Raw materials

Imidazole

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