HARMALINE

HARMALINE
  • CAS No.:304-21-2
Other grades of this product :
HARMALINE Basic information
Product Name:HARMALINE
Synonyms:1-METHYL-7-METHOXY-3,4-DIHYDRO-BETA-CARBOLINE;TIMTEC-BB SBB003407;1-Methyl-7-methoxy-3,4-dihydroxy-beta-carboline;1-methyl-7-methoxy-3,4-dihydro-β-carboline;HARMALINE(EXTRACTFORMPEGANUMHARMALAROOTS);3,4-Dihydro-7-methoxy-1-methyl-beta-carboline 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole Dihydroharmine;NSC 407285;PYRIDE(3,4-B)INDOLE,4,9-DIHYDRO-7-METHOXY-1-METHYL-
CAS:304-21-2
MF:C13H14N2O
MW:214.26
EINECS:206-152-6
Product Categories:Inhibitors;Indoles and derivatives;Heterocyclic Compounds
Mol File:304-21-2.mol
HARMALINE Chemical Properties
Melting point 232-234 °C(lit.)
Boiling point 354.4°C (rough estimate)
alpha ±0°
density 1.0850 (rough estimate)
refractive index 1.6450 (estimate)
Water Solubility Slightly soluble in water
form powder
pka4.2(at 25℃)
color Light orange to Yellow to Green
Merck 14,4613
BRN 207310
CAS DataBase Reference304-21-2(CAS DataBase Reference)
NIST Chemistry ReferenceHarmaline(304-21-2)
EPA Substance Registry System3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl- (304-21-2)
Safety Information
Hazard Codes Xn
Risk Statements 25-20/21/22
Safety Statements 22-24/25-36
RIDADR 1544
WGK Germany 3
RTECS UU9800000
HazardClass 6.1(b)
PackingGroup III
Hazardous Substances Data304-21-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
HARMALINE Usage And Synthesis
UsesCNS stimulant, antiparkinsonian agent
UsesCNS stimulant; may act through NMDA receptors. Reversible inhibitor of MAO-A
DefinitionChEBI: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Synthesis Reference(s)Canadian Journal of Chemistry, 37, p. 1851, 1959 DOI: 10.1139/v59-272
Purification MethodsRecrystallise harmaline from MeOH and sublime it at high vacuum. It has UV in MeOH a

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