| Nicotinic acid N-oxide Basic information |
| Description Preparation |
| Product Name: | Nicotinic acid N-oxide |
| Synonyms: | 3-carboxypyridine 1-oxide;Nicotinic Acid N-Oxide;Nicotinic acid N-oxide 99%;1-oxidopyridin-1-ium-3-carboxylic acid;TIMTEC-BB SBB004182;N-oxidenicotinic acid;Oxiniacic acid~Pyridine-3-carboxylic acid N-oxide;Nicotinic N-oxide |
| CAS: | 2398-81-4 |
| MF: | C6H5NO3 |
| MW: | 139.11 |
| EINECS: | 219-265-0 |
| Product Categories: | C6;Heterocyclic Building Blocks;Heterocyclic Compounds;Pyridines;NOVACYL |
| Mol File: | 2398-81-4.mol |
| Nicotinic acid N-oxide Chemical Properties |
| Melting point | 254-255 °C (dec.)(lit.) |
| Boiling point | 255.04°C (rough estimate) |
| density | 1.4429 (rough estimate) |
| refractive index | 1.5423 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | benzene: insoluble |
| form | Fine Crystalline Powder |
| pka | 3.19±0.10(Predicted) |
| color | Beige |
| Merck | 14,6941 |
| BRN | 115860 |
| CAS DataBase Reference | 2398-81-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Pyridinecarboxylic acid, 1-oxide(2398-81-4) |
| EPA Substance Registry System | 3-Pyridinecarboxylic acid, 1-oxide (2398-81-4) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21-36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| HS Code | 29333999 |
| MSDS Information |
| Provider | Language |
|---|---|
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Nicotinic acid N-oxide Usage And Synthesis |
| Description | Nicotinic acid N-oxide is an organic compound with the formula (HO2C)C5H4NO. It is the N-oxide of nicotinic acid ((HO2C)C5H4N).The compound is a precursor to the popular drugs niflumic acid and pranoprofen. |
| Preparation | Nicotinic acid N-oxide is prepared by oxidation of nicotinic acid or the hydrolysis of 3-cyanopyridine N-oxide. |
| Chemical Properties | BEIGE FINE CRYSTALLINE POWDER |
| Uses | antilipemic |
| Uses | Nicotinic acid N-oxide was used in a study to develop liquid chromatographic method for determination of free nicotinic acid and its metabolites in plasma and urine. It was used to synthesize and characterize peroxo complexes of vanadium(V) and molybdenum (VI) with nicotinic acid and nicotinic acid N-oxide. |
| General Description | Nicotinic acid N-oxide acts as a ligand and forms lead-carboxylate complexes having phosphorescent properties. |
| Nicotinic acid N-oxide Preparation Products And Raw materials |
| Preparation Products | 2-Chloronicotinic acid-->2-Aminonicotinic acid-->6-Aminonicotinic acid-->2-ACETONICOTINIC ACID-->2-Hydroxy-5-pyridinecarboxylic acid-->2-Hydroxynicotinic acid |
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