Other grades of this product :
| D(+)-Phenylalaninol Basic information |
| D(+)-Phenylalaninol Chemical Properties |
| Melting point | 93-95 °C(lit.) | | Boiling point | 122 °C / 4mmHg | | alpha | 23 º (c=1.2, 1 N HCl 22 ºC) | | density | 1.0406 (rough estimate) | | refractive index | 23.5 ° (C=1.2, 1mol/L HCl) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Soluble in Dichloromethane, Ethyl Acetate, Methanol. | | form | Crystalline Powder and Chunks | | pka | 12.85±0.10(Predicted) | | color | White to yellow | | optical activity | [α]/D +22.8°, c = 1.2 in 1 M HCl | | Sensitive | Air Sensitive | | BRN | 4665408 | | CAS DataBase Reference | 5267-64-1(CAS DataBase Reference) |
| Hazard Codes | C,Xi | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45-27 | | RIDADR | UN 3259 8/PG 3 | | WGK Germany | 3 | | F | 10-23 | | HazardClass | IRRITANT | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29221990 |
| D(+)-Phenylalaninol Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. | | Uses | D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins. | | Purification Methods | It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.] |
| D(+)-Phenylalaninol Preparation Products And Raw materials |
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