[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester

[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester
  • CAS No.:379270-35-6
Other grades of this product :

[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Basic information
Appearance
Product Name:[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester
Synonyms:[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester;Tenofovir Related Compound 2;phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate;GS7340 impurity1;GS7340 intermediate 1;phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate;phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate;Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate
CAS:379270-35-6
MF:C15H18N5O4P
MW:363.31
EINECS:807-851-4
Product Categories:Intermediate
Mol File:379270-35-6.mol
[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Chemical Properties
Melting point 237-239°C
Boiling point 610.1±65.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
pka2.09±0.10(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Usage And Synthesis
AppearanceWhite powder
Uses[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
Application[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Preparation Products And Raw materials
Raw materialsDIPHENYLIODIUM FLUORIDE-->DIPHENYLIODONIUM HEXAFLUOROARSENATE-->Tenofovir-->DIPHENYLIODONIUM BROMIDE-->DIPHENYL PHOSPHITE-->DIPHENYLIODONIUM TRIFLUOROMETHANESULFONATE-->Phenol-->Triphenyl phosphite

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