(S)-Oxiranemethanol

(S)-Oxiranemethanol
  • CAS No.:60456-23-7
Other grades of this product :
(S)-Oxiranemethanol Basic information
Product Name:(S)-Oxiranemethanol
Synonyms:(S)-(-)-GLYCIDOL ((S)-(-)-2,3-EPOXY-1-PROPANOL);[(2r)-oxiran-2-yl]methanol;(S)-(-)-GLYCIDOL, 97% (98% EE/GLC);S-Glycidoe;(R)-3-Hydroxy-1,2-epoxypropane;(S)-(-)-2,3-Epoxy-1-propanol, (S)-(-)-Oxirane-2-methanol;(S)-(-)-Glycidol, (98% ee), 97%;(2S)-(-)-3-Hydroxy-1,2-propenoxide 97%
CAS:60456-23-7
MF:C3H6O2
MW:74.08
EINECS:
Product Categories:Chiral Compound;CHIRAL COMPOUNDS;chiral;API intermediates
Mol File:60456-23-7.mol
(S)-Oxiranemethanol Chemical Properties
Melting point 72-73 °C
alpha -15 º (neat)
Boiling point 66-67 °C19 mm Hg(lit.)
density 1.116 g/mL at 20 °C(lit.)
refractive index n20/D 1.433(lit.)
Fp 178 °F
storage temp. -20°C
solubility Soluble in chloroform, DMSO and methanol.
pka14.62±0.10(Predicted)
form Liquid
color Pale yellow
optical activity[α]20/D 15°, neat
BRN 79783
InChIKeyCTKINSOISVBQLD-VKHMYHEASA-N
CAS DataBase Reference60456-23-7(CAS DataBase Reference)
NIST Chemistry ReferenceOxiranemethanol, (S)-(60456-23-7)
Safety Information
Hazard Codes T
Risk Statements 45-60-21/22-23-36/37/38-68-41-37/38
Safety Statements 53-45-36/37/39-26
RIDADR UN 2810 6.1/PG 2
WGK Germany 3
RTECS RR0508100
10-21
HazardClass 6.1
PackingGroup III
HS Code 29109000
MSDS Information
ProviderLanguage
[(2R)-Oxiran-2-yl]methanol English
SigmaAldrich English
(S)-Oxiranemethanol Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
UsesEmployed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.
General DescriptionGlycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters,?polycarbonates,?polyurethanes,?and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.
Purification Methods[S(-)-isomer, § also available on polymer support, has b 49-50o/7mm, 66-67o/19mm, [ ] D -1 5o(neat)], [R(+)-isomer has b 56 -5 6 . 5o/11mm, d 4 1.117, n D 1.429, [ ] D +15o (neat)]. Purify glycidol by fractional distillation.

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