Product

1,2,4-Trimethoxybenzene

CAS No.：135-77-3

Other grades of this product :

1,2,4-Trimethoxybenzene Basic information

Product Name:	1,2,4-Trimethoxybenzene
Synonyms:	HYDROXYHYDROQUINONE TRIMETHYL ETHER;1,2,4-TRIMETHOXYBENZENE;1,2,4-Trimethoxybenzol;cerium(3+) phosphate;1,2,4-trimethoxy-benzen;Benzene, 1,2,4-trimethoxy-;1.2.4-Trimethoxy benzone;1,2,4-Benzenetriol trimethyl ether
CAS:	135-77-3
MF:	C9H12O3
MW:	168.19
EINECS:	205-219-7
Product Categories:	Building Blocks;C9;Chemical Synthesis;Ethers;Organic Building Blocks;Oxygen Compounds;Aromatic Hydrocarbons (substituted) & Derivatives;Benzene derivates;Anisoles, Alkyloxy Compounds & Phenylacetates;bc0001
Mol File:	135-77-3.mol

1,2,4-Trimethoxybenzene Chemical Properties

Boiling point	247 °C(lit.)
density	1.126 g/mL at 25 °C(lit.)
refractive index	n20/D 1.533(lit.)
Fp	>230 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform, Ethyl Acetate
form	Oil
color	Clear Colourless
Water Solubility	Not miscible in water.
Merck	14,1073
BRN	2047579
CAS DataBase Reference	135-77-3(CAS DataBase Reference)
NIST Chemistry Reference	1,2,4-Trimethoxybenzene(135-77-3)
EPA Substance Registry System	1,2,4-Trimethoxybenzene (135-77-3)

Safety Information

Hazard Codes	Xi
Safety Statements	23-24/25
WGK Germany	3
RTECS	DC2770000
Hazard Note	Irritant
TSCA	Yes
HS Code	29093090

MSDS Information

Provider	Language
1,2,4-Trimethoxybenzene	English
SigmaAldrich	English
ACROS	English
ALFA	English

1,2,4-Trimethoxybenzene Usage And Synthesis

Chemical Properties	clear light yellow to yellow-brown liquid
Uses	1,2,4-Trimethoxybenzene is used as a reagent in the synthesis of barbigerone derivatives which can be used as antiproliferative and antiangiogenesis agents. Also used as a reagent in the synthesis of Malvone A (M161525) which is a phytoalexin found in Malva sylvestris.

1,2,4-Trimethoxybenzene Preparation Products And Raw materials

Raw materials	Hydrogen peroxide-->Dimethyl sulfate-->Sodium dichromate dihydrate-->Hydroquinone-->Vanillin-->1,2,4-Triacetoxybenzene
Preparation Products	2,4,5-Trimethoxynitrobenzene -->BENZENE,1,2,4-TRIMETHOXY-5-(2-PROPENYL)--->METHOXYBENZOQUINONE

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