Etamsylate

CAS No.：2624-44-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Etamsylate Basic information

Product Name:	Etamsylate
Synonyms:	altodor;e141;eselin;md141;2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine;2,5-dihydroxy-benzenesulfonicacicompd.withn-ethylethanamine(1:1);2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine;2,5-DihydroxybenzenesulfonicacidcompdwithN-ethylethanamine
CAS:	2624-44-4
MF:	C10H17NO5S
MW:	263.31
EINECS:	220-090-7
Product Categories:	Other APIs;For the prevention and treatment of bleeding before surgery, but for intestinal bleeding, bleeding and urinary tract bleeding, etc;Amines;Aromatics;Intermediates & Fine Chemicals;API;Pharmaceuticals;Sulfur & Selenium Compounds;2624-44-4
Mol File:	2624-44-4.mol

Etamsylate Chemical Properties

Melting point	125°
density	1.3441 (rough estimate)
refractive index	1.5060 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
form	neat
color	White to Pale Red
Merck	14,3722
Stability:	Hygroscopic
InChIKey	HBGOLJKPSFNJSD-UHFFFAOYSA-N
CAS DataBase Reference	2624-44-4(CAS DataBase Reference)
EPA Substance Registry System	Ethamsylate (2624-44-4)

Safety Information

RTECS	DB6145000
HazardClass	IRRITANT
Toxicity	LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)

MSDS Information

Provider	Language
Etamsylate	English

Etamsylate Usage And Synthesis

Chemical Properties	White Solid
Uses	Haemostatic / Anti Coagulant
Uses	Hemostatic.
Uses	Hemostatic;prostaglandin synthesis inhibitor
Clinical Use	Short-term treatment of blood loss in menorrhagiaProphylaxis of surgical bleeding (unlicensed)
Drug interactions	Potentially hazardous interactions with other drugs None known
Metabolism	Etamsylate is excreted unchanged, mainly in the urine.

Etamsylate Preparation Products And Raw materials

Raw materials

Diethylamine-->Sulfur dioxide-->1,4-Benzoquinone-->Diethylaminoethanol

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