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| 4-methoxy-3-methylaniline Basic information |
| Product Name: | 4-methoxy-3-methylaniline | | Synonyms: | 4-AMino-2-Methylanisole[4-Methoxy-3-Methylaniline];3-Methyl-4-methoxybenzenamine;4-AMINO-2-METHYLANISOLE;4-METHOXY-3-METHYLANILINE;3-Methyl-4-methoxyaniline;4-methoxy-3-methylbenzenamine;BenzenaMine, 4-Methoxy-3-Methyl-;4-AMINO-24-AMINO-2-METHYLANISOLE-METHYLANISOLE | | CAS: | 136-90-3 | | MF: | C8H11NO | | MW: | 137.18 | | EINECS: | | Product Categories: | | Mol File: | 136-90-3.mol |
| 4-methoxy-3-methylaniline Chemical Properties |
| Melting point | 57-60℃ | | Boiling point | 252.03°C (rough estimate) | | density | 1.0630 (rough estimate) | | refractive index | 1.5360 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 5.32±0.10(Predicted) | | color | Dark Red to Black |
| 4-methoxy-3-methylaniline Usage And Synthesis |
| Uses | 4-Methoxy-3-methylaniline is used in preparation of triamine pyrimidine derivatives as antitumor agents. | | Synthesis | The synthesis of 4-methoxy-3-methylaniline is as follows:4-Methoxy-3-methyl-phenylamine10% Palladium on carbon (10% Pd/C) (1.5 g) was added to a solution of 1 -methoxy-2- methyl-4-nitrobenzene (9.5 g, 57 mmol) in methanol (100 ml_). The mixture was stirred under a hydrogen atmosphere (1 atm.) at room temperature for 16 h. The mixture was filtered through a pad of CELITE and the filtrate was evaporated in vacuo to yield 4- methoxy-3-methylphenylamine (8.0 g, 57 mmol, 100%). |
| 4-methoxy-3-methylaniline Preparation Products And Raw materials |
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