Product

N-Succinimidyl-N-methylcarbamate

CAS No.：18342-66-0

Other grades of this product :

N-Succinimidyl-N-methylcarbamate Basic information

Product Name:	N-Succinimidyl-N-methylcarbamate
Synonyms:	2,5-PYRROLIDINEDIONE, 1-[[(METHYLAMINO)CARBONYL]OXY]-;N-SUCCINIMDYL-N-METHYLCARBAMATE;N-SUCCINIMIDYL-N-METHYLCARBAMATE;N-Succinimidyl-N-methylcarbama;methyl isocyanate substitute;Methyl isocyanate substitute, MIC substitute;2,5-dioxopyrrolidin-1-yl MethylcarbaMate;SuO-NM
CAS:	18342-66-0
MF:	C6H8N2O4
MW:	172.14
EINECS:
Product Categories:	Norbornene Derivatives;Medical Intermediates
Mol File:	18342-66-0.mol

N-Succinimidyl-N-methylcarbamate Chemical Properties

Melting point	148-153 °C
density	1.41±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Dichloromethane (Slightly), DMSO (Slightly)
pka	11.00±0.46(Predicted)
form	Solid
color	White to Off-White
Water Solubility	Slightly soluble in water.
Sensitive	Moisture Sensitive
BRN	1531863
CAS DataBase Reference	18342-66-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
F	10-21

MSDS Information

Provider	Language
SigmaAldrich	English

N-Succinimidyl-N-methylcarbamate Usage And Synthesis

Uses

N-Succinimidyl N-Methylcarbamate is used as a reagent in the synthesis of Argifin, a natural product chitinase inhibitor with chemotherapeutic potential. N-Succinimidyl N-Methylcarbamate is also used as a reagent in the preparation of 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide (A616300); a metabolite of Temozolomide (T017775) which is an imidazotetrazine alkylating agent and antineoplastic.

N-Succinimidyl-N-methylcarbamate Preparation Products And Raw materials

Preparation Products

5-(Amino-1-(N-methyl Carbamoyl)

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