(S)-4-Chloro-3-hydroxybutyronitrile

(S)-4-Chloro-3-hydroxybutyronitrile
  • CAS No.:127913-44-4
Other grades of this product :
(S)-4-Chloro-3-hydroxybutyronitrile Basic information
Product Name:(S)-4-Chloro-3-hydroxybutyronitrile
Synonyms:4-CHLORO-3-HYDROXY-BUTYRONITRILE;(S)-(-)-4-CHLORO-3-HYDROXYBUTYRONITRILE;(S)-4-CHLORO-3-HYDROXYBUTYRONITRILE;(S)-(-)-4-CHLORO-3-HYDROXYBUTYRONITRILE, 97% (97% EE/GLC);(S)-4-CHLORO-3-HYDROXYBUTYRONITRILE 98+%;(S)-4-chloro-3-hydroxybutanenitrile;(3S)-4-chloro-3-hydorxybutyronitrile;(3S)-4-Chloro-3-hydroxybutyronitrile
CAS:127913-44-4
MF:C4H6ClNO
MW:119.55
EINECS:1308068-626-2
Product Categories:chiral
Mol File:127913-44-4.mol
(S)-4-Chloro-3-hydroxybutyronitrile Chemical Properties
Boiling point 110 °C/1 mmHg(lit.)
density 1.250 g/mL at 20 °C(lit.)
refractive index n20/D 1.474(lit.)
Fp 110 °C
storage temp. 2-8°C
solubility Chloroform (Sparingly), Methanol (Slightly)
pka12.67±0.20(Predicted)
form Oil
color Clear Colourless
CAS DataBase Reference127913-44-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
HS Code 29269090
MSDS Information
ProviderLanguage
(S)-4-Chloro-3-hydroxybutyronitrile English
(S)-4-Chloro-3-hydroxybutyronitrile Usage And Synthesis
Chemical PropertiesColorless to light yellow liqui
Uses(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparat ion of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
Uses(3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.
(S)-4-Chloro-3-hydroxybutyronitrile Preparation Products And Raw materials
Raw materials(R)-(-)-Epichlorohydrin-->(S)-(+)-Epichlorohydrin-->4-CHLORO-3-HYDROXY BUTYRONITRILE
Preparation ProductsButanenitrile, 3,4-dihydroxy-, (3R)--->(R)-4-Chloro-3-hydroxybutyronitrile

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