Other grades of this product :
| Hydrocortisone-17-butyrate Basic information |
| Product Name: | Hydrocortisone-17-butyrate | | Synonyms: | HYDROCORTISONE 17-BUTYRATE;HYDROCORTISONE BUTYRATE;CORTISOL 17-BUTYRATE;11b,17,21-trihydroxypregn-4-ene-3,20-dione 17-butyrate;11BETA,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE 17-BUTYRATE;11-beta,17-alpha,21-trihydroxy-4-pregnene-3,20-dione17-alpha-butyrate;h.17b;hb(sub17) | | CAS: | 13609-67-1 | | MF: | C25H36O6 | | MW: | 432.56 | | EINECS: | 237-093-4 | | Product Categories: | NOVANTRONE;Steroid and Hormone;Steroids | | Mol File: | 13609-67-1.mol |
| Hydrocortisone-17-butyrate Chemical Properties |
| Melting point | 210.0 to 214.0 °C | | Boiling point | 466.2°C (rough estimate) | | density | 1.0914 (rough estimate) | | refractive index | 1.4593 (estimate) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | neat | | pka | 12.98±0.10(Predicted) | | color | White to Off-White | | Merck | 14,4787 | | CAS DataBase Reference | 13609-67-1(CAS DataBase Reference) |
| WGK Germany | 2 | | RTECS | GM9002000 | | HS Code | 2937290000 |
| Hydrocortisone-17-butyrate Usage And Synthesis |
| Uses | antineoplastic | | Uses | Hydrocortisone Butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent. | | Uses | Hydrocortisone-17-butyrate is a topical corticosteroid with anti-inflammatory properties; marker for topical corticosteroid allergy. | | Definition | ChEBI: Cortisol esterified with butyric acid at the 17-hydroxy group. | | Brand name | Locoid (Ferndale); Locoid (Yamanouchi). | | Biochem/physiol Actions | Hydrocortisone 17-butyrate is a corticosteroid that acts as a dermocorticoid due to its application in dermatological therapy. It exhibits therapeutic effects against vitiligo of the face and neck. | | Contact allergens | Hydrocortisone 17-butyrate is a C 17 ester of hydrocorti-
sone. It represents the D2 group of corticosteroids, non
C 16 methylated with a C 17 ester: hydrocortisone
17-butyrate, hydrocortisone 17-valerate, hydrocortisone
aceponate (17-propionate and 21-acetate), methylpred-
nisolone aceponate, and prednicarbate. It is sometimes
hydrolyzed in vivo into hydrocortisone, giving allergic
reactions to group-A-sensitized people. |
| Hydrocortisone-17-butyrate Preparation Products And Raw materials |
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