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| VALNEMULIN Basic information |
| Product Name: | VALNEMULIN | | Synonyms: | VALNEMULIN;2-[[2-[[(2R)-2-Amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]acetic Acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyldecahydro-5-hydroxy-4,6,9,10- tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl Ester;supplier valnemulin;Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester | | CAS: | 101312-92-9 | | MF: | C31H52N2O5S | | MW: | 564.82 | | EINECS: | 1312995-182-4 | | Product Categories: | API;Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Alphabetic;Antibiotics;Chemical Structure;OthersAnalytical Standards;V;Diterpenes antibiotic | | Mol File: | 101312-92-9.mol |
| VALNEMULIN Chemical Properties |
| Melting point | 140-143°C | | Boiling point | 672.7±55.0 °C(Predicted) | | density | 1.13±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 14.65±0.70(Predicted) |
| VALNEMULIN Usage And Synthesis |
| Description | Valnemulin is a broad-spectrum pleuromutilin antibiotic that binds to peptidyl transferase in the 50S ribosomal subunit. It has been used in veterinary medicine to treat swine diseases including, B. hyodysenteriae and M. hyopneumoniae. | | Chemical Properties | White to Off-White Solid | | Uses | Semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial | | Uses | Valnemulin is a semi-synthetic pleuromutilin prepared by sequential reaction of pleuromutilin tosylate with 2-amino-1,1-dimethylethylthiol, coupling the free amine with a protected valine and then deprotection to provide the final product. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA. |
| VALNEMULIN Preparation Products And Raw materials |
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