Carbobenzoxyhydrazide

Carbobenzoxyhydrazide
  • CAS No.:5331-43-1
Other grades of this product :
Carbobenzoxyhydrazide Basic information
Product Name:Carbobenzoxyhydrazide
Synonyms:hydrazinecarboxylicacid,phenymethylester;phenymethylhydrazinecarboxylate;Phenylmethyl N-aminocarbamate;Carbobenzoxyhydrazide,98%;Carbobenzoxyhydrazid;Carbobenzyloxyhydrazine;Hydrazincarboxylic Acid Benzyl Ester;NSC 2287
CAS:5331-43-1
MF:C8H10N2O2
MW:166.18
EINECS:226-230-3
Product Categories:Phosgene Derivatives
Mol File:5331-43-1.mol
Carbobenzoxyhydrazide Chemical Properties
Melting point 65-68 °C (lit.)
Boiling point 294.38°C (rough estimate)
density 1.2265 (rough estimate)
refractive index 1.6180 (estimate)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO, Methanol
form Solid
pka10.56±0.20(Predicted)
color Beige
Water Solubility Soluble in water (slightly), methanol and DMSO.
BRN 1952982
InChIKeyRXUBZLMIGSAPEJ-UHFFFAOYSA-N
CAS DataBase Reference5331-43-1(CAS DataBase Reference)
NIST Chemistry ReferenceHydrazinecarboxylic acid, phenylmethyl ester(5331-43-1)
EPA Substance Registry SystemHydrazinecarboxylic acid, phenylmethyl ester (5331-43-1)
Safety Information
Hazard Codes Xi
Risk Statements 41
Safety Statements 26-36
WGK Germany 3
RTECS MV1724950
TSCA Yes
HS Code 29280000
MSDS Information
ProviderLanguage
Carbobenzoxyhydrazide English
SigmaAldrich English
ACROS English
ALFA English
Carbobenzoxyhydrazide Usage And Synthesis
Chemical PropertiesLIGHT BEIGE SHINY FLAKES
UsesBenzyl Carbazate has been shown to prevent the occurrence of oligonucleosome-sized DNA fragmentation in the cell-free system.
UsesBenzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.
Carbobenzoxyhydrazide Preparation Products And Raw materials
Preparation Productstert-Butyl 4-hydrazinylpiperidine-1-carboxylate

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