(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine

CAS No.：132335-46-7

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(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine Basic information

Product Name:	(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
Synonyms:	S-(+)-N,N-DIMETHYL-3-(1-NAPHTHENYLOXY)-3-(2-THIENYL)PROPANAMINE;(S)-(+)-N,N-DIMETHYL-3-(1-NAPHTHALENYLOXY)-3-(2-THIENYL)PROPANAMINE,ENTERPRISE STANDARD;N-Methyl Duloxetine;(S)-(+)-N,N-Dimethyl-3-(1-phthalenyloxy)-3-(2-thienyl)propamine;N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;(3S)-N,N-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine;Duloxetine Impurity 11;(s)-(+)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
CAS:	132335-46-7
MF:	C19H21NOS
MW:	311.44
EINECS:
Product Categories:	Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:	132335-46-7.mol

(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine Chemical Properties

Boiling point	459.7±40.0 °C(Predicted)
density	1.146
storage temp.	2-8°C
pka	9.19±0.28(Predicted)
CAS DataBase Reference	132335-46-7(CAS DataBase Reference)

Safety Information

MSDS Information

(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine Usage And Synthesis

Chemical Properties	White powder
Uses	A duloxetine impurity.

(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine Preparation Products And Raw materials

Raw materials	(3S)-N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine tartrate-->2-Thiophenepropanamine, N,N-dimethyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1)-->S-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)-1-propylamine oxalate-->CARBON DIOXIDE-->(S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine-->Formaldehyde-->1-Fluoronaphthalene
Preparation Products	(R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine

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