TriMethyl(broModifluoroMethyl)silane

TriMethyl(broModifluoroMethyl)silane
  • CAS No.:115262-01-6
Other grades of this product :
TriMethyl(broModifluoroMethyl)silane Basic information
Product Name:TriMethyl(broModifluoroMethyl)silane
Synonyms:(Bromodifluoromethyl)trimethylsilane 98%;TriMethyl(broModifluoroMethyl)silane;(BroModifluoroMethyl)triMethylsilane;Trimethyl(bromodifluoromethyl)silane 97%;Bromodifluoro(trimethylsilyl)methane;(Bromodifluoromethyl);(Bromodifluoromethyl)trimethylsilane >Silane, (bromodifluoromethyl)trimethyl-
CAS:115262-01-6
MF:C4H9BrF2Si
MW:203.1
EINECS:806-938-4
Product Categories:
Mol File:115262-01-6.mol
TriMethyl(broModifluoroMethyl)silane Chemical Properties
Boiling point 108°C(lit.)
density 1.306
refractive index n/D1.407
Fp 46℃
storage temp. -20°C
form liquid
color clear
InChIKeyWDZVWBWAUSUTTO-UHFFFAOYSA-N
CAS DataBase Reference115262-01-6
Safety Information
Risk Statements 11
Safety Statements 24/25
RIDADR UN 1993C 3 / PGIII
TSCA No
HazardClass 3
PackingGroup II
HS Code 29319090
MSDS Information
TriMethyl(broModifluoroMethyl)silane Usage And Synthesis
UsesNovel difluorocarbene source for the efficient difluoromethylenation of alkenes/alkynes and difluoromethylation of O-, S-, and N-nucleophiles.
UsesTrimethyl(bromodifluoromethyl)silane can be used as neuroactive steroids.
UsesAs reported by Hu and co-workers, (Bromodifluoromethyl)trimethylsilane is a highly useful reagent for the formation of difluoromethene-containing 3-membered rings and can also difluoromethylate heteroatoms with the assistance of alkaline bases, most effectively KOH.
General Description(Bromodifluoromethyl)trimethylsilane (TMSCF2Br) is commonly used as a source to generate dilfluorocarbene. TMSCF3 (Ruppert–Prakash reagent) and BBr3 undergoes fast halogen–exchange reaction to form MSCF2Br.

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