4-(Trifluoromethoxy)benzyl bromide

4-(Trifluoromethoxy)benzyl bromide
  • CAS No.:50824-05-0
Other grades of this product :
4-(Trifluoromethoxy)benzyl bromide Basic information
Uses
Product Name:4-(Trifluoromethoxy)benzyl bromide
Synonyms:4-(TRIFLUOROMETHOXY)BENZYL BROMIDE;ALPHA-BROMO-4-(TRIFLUOROMETHOXY)TOLUENE;1-(BROMOMETHYL)-4-(TRIFLUOROMETHOXY)BENZENE;TIMTEC-BB SBB006578;P-TritluromethoxybenzylBromide;4-(Trifluoromethoxy)benzyl;4-(Trifluoromethoxy)benzyl bromide 97%;4-(Trifluoromethoxy)benzylbromide97%
CAS:50824-05-0
MF:C8H6BrF3O
MW:255.03
EINECS:
Product Categories:Aromatic Halides (substituted);Miscellaneous;Ethers;Organic Building Blocks;Oxygen Compounds;Trifluoro-methoxy-benzene series
Mol File:50824-05-0.mol
4-(Trifluoromethoxy)benzyl bromide Chemical Properties
Melting point 22-24°C
Boiling point 82-84 °C10 mm Hg(lit.)
density 1.594 g/mL at 25 °C(lit.)
refractive index n20/D 1.48(lit.)
Fp 202 °F
storage temp. Refrigerated.
form Liquid or Low Melting Solid
Specific Gravity1.594
color Clear faintly yellow
Sensitive Lachrymatory
BRN 2521451
CAS DataBase Reference50824-05-0(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-27-28-36/37/39-45
RIDADR UN 3265 8/PG 2
WGK Germany 3
Hazard Note Corrosive/Lachrymatory
HazardClass 8
PackingGroup III
HS Code 29093090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
4-(Trifluoromethoxy)benzyl bromide Usage And Synthesis
Uses4-Trifluoromethoxybenzyl Bromide is a useful synthetic intermediate. It is used to prepare (nitro)[(trifluoromethoxy)benzyloxy]dihydroimidazo[2,1-b][1,3]oxazines with antitubercular activities. It is also used to synthesize tetrahydronaphthalenols with anti-allergic activities.
Chemical PropertiesColorless to light yellow liqui
Uses4-(Trifluoromethoxy)benzyl bromide may be used in the synthesis of bioreductive drug, (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824).
General DescriptionPolymerizations of 4-(trifluoromethoxy)benzyl bromide, via Friedel-Crafts polymerization using aluminum chloride as a catalyst has been reported.
4-(Trifluoromethoxy)benzyl bromide Preparation Products And Raw materials
Preparation Products4-(Trifluoromethyl)phenylacetic acid-->4-(Trifluoromethoxy)benzoic acid

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