Product

2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE

CAS No.：723286-98-4

Other grades of this product :

2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Basic information

Product Name:	2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE
Synonyms:	2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE;5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole;1,3,4-Oxadiazole, 2-(chlo...;1,3,4-Oxadiazole, 2-(chloroMethyl)-5-(trifluoroMethyl)-;2-Chloromethyl-5-trifluoromethyl trifluoromethyl -[1,3,4]oxadiazole;Sitagliptin Impurity 65;2-(Chloromethyl)-5-(trifluromethyl)-1,3,4-oxadiazole
CAS:	723286-98-4
MF:	C4H2ClF3N2O
MW:	186.52
EINECS:
Product Categories:	Heterocycles;Intermediates;Heterocyclic Compounds;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	723286-98-4.mol

2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Chemical Properties

Boiling point	55-60 °C(Press: 10 Torr)
density	1.555±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	Chloroform (Soluble), Methanol (Sparingly)
pka	-8.11±0.44(Predicted)
form	Oil
color	Pale Yellow to Yellow
CAS DataBase Reference	723286-98-4

Safety Information

HS Code

2929900090

MSDS Information

2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Usage And Synthesis

Chemical Properties	Yellow Liquid
Uses	Sitagliptin intermediate. An anti-hypertensive agent for the treatment of diabetes and hypertension.

2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE Preparation Products And Raw materials

Raw materials

1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine-->TRIFLUOROACETIC ACID HYDRAZIDE-->Chloroacetyl chloride-->Trifluoroacetic anhydride

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