| 4'-HYDROXY-2'-METHYLACETOPHENONE Basic information |
| Product Name: | 4'-HYDROXY-2'-METHYLACETOPHENONE |
| Synonyms: | 4''-HYDROXY-2''-METHYLACETOPHENONE 97%;2-Methyl-4-hydroxybenzaldehyde;1-(4-hydroxy-2-Methylphenyl)ethan-1-one;4'-HYDROXY-2'-METHYLACETOPHENONE;4-HYDROXY-2-METHYLACETOPHENONE;4-ACETYL-3-METHYLPHENOL;2-METHYL-4-HYDROXYACETOPHENONE;1-(4-Hydroxy-2-methylphenyl)ethanone |
| CAS: | 875-59-2 |
| MF: | C9H10O2 |
| MW: | 150.17 |
| EINECS: | 212-874-2 |
| Product Categories: | C9;Carbonyl Compounds;Aromatic Acetophenones & Derivatives (substituted);Ketones |
| Mol File: | 875-59-2.mol |
| 4'-HYDROXY-2'-METHYLACETOPHENONE Chemical Properties |
| Melting point | 129-131 °C(lit.) |
| Boiling point | 313 °C(lit.) |
| density | 1.059 g/mL at 25 °C(lit.) |
| refractive index | 1.5369 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| pka | 8.28±0.18(Predicted) |
| form | Powder or Crystals |
| color | Off-white to beige to tan |
| Specific Gravity | 1.059 |
| CAS DataBase Reference | 875-59-2(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39-36 |
| WGK Germany | 3 |
| HS Code | 29145090 |
| MSDS Information |
| Provider | Language |
|---|---|
| ACROS | English |
| SigmaAldrich | English |
| 4'-HYDROXY-2'-METHYLACETOPHENONE Usage And Synthesis |
| Chemical Properties | off-white to beige crystalline powder |
| Uses | 4''-Hydroxy-2''-methylacetophenone has been used in the preparation of morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity. |
| Definition | ChEBI: A member of the class of acetophenones that is acetophenone substituted by a hydroxy group at position 4 and a methyl group at position 2 respectively. |
| Preparation | Preparation by dealkylation of 4-hydroxy-2-methyl-5-iso-propylacetophenone with aluminium chloride in chlorobenzene at 50° (80%). |
| 4'-HYDROXY-2'-METHYLACETOPHENONE Preparation Products And Raw materials |
| Preparation Products | 4-HYDROXY-2-METHYLBENZOIC ACID 98-->5-Hydroxy-1-indanone |
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