| (R)-1-Boc-3-Hydroxypiperidine Basic information |
| Product Name: | (R)-1-Boc-3-Hydroxypiperidine |
| Synonyms: | (R)-1-Boc-3-hydroxypiperidine 95%;tert-Butyl (3R)-3-hydroxypiperidine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine;tert- butyl (R)-3-hydroxy piperidine-1-carboxylate;(R)-1-Boc-3-hydroxypiperidine,97%;(R)-1-N-BOC-3-HYDROXYPIPERIDINE;(R)-1-BOC-3-PIPERIDINOL;(R)-1-BOC-3-HYDROXYPIPERIDINE;R-3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE |
| CAS: | 143900-43-0 |
| MF: | C10H19NO3 |
| MW: | 201.26 |
| EINECS: | |
| Product Categories: | Ibrutinib intermediate;Piperazine;Piperidine;Piperidines |
| Mol File: | 143900-43-0.mol |
| (R)-1-Boc-3-Hydroxypiperidine Chemical Properties |
| Melting point | 43-50 °C |
| Boiling point | 292.3±33.0 °C(Predicted) |
| density | 1.107±0.06 g/cm3(Predicted) |
| Fp | 104°C |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| pka | 14.74±0.20(Predicted) |
| form | Low Melting Solid |
| color | White to tan |
| optical activity | [α]/D 22±3°, c = 5 in methanol |
| InChIKey | UIJXHKXIOCDSEB-MRVPVSSYSA-N |
| CAS DataBase Reference | 143900-43-0(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T |
| Risk Statements | 36/37/38-41-37/38-25 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 29333990 |
| MSDS Information |
| (R)-1-Boc-3-Hydroxypiperidine Usage And Synthesis |
| Chemical Properties | White powder |
| Uses | (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors. |
| (R)-1-Boc-3-Hydroxypiperidine Preparation Products And Raw materials |
| Preparation Products | (S)-3-Amino-1-N-Boc-piperidine-->(3R)-1-Boc-3-(4-aMino-3-iodo-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidine |
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