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| (2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Basic information |
| Product Name: | (2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER | | Synonyms: | (2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-butyl (2S,5R)-2,5-diMethylpiperazine-1-carboxylate;(2S,5R)-1-Boc-2,5-diMethylpiperazine-HCl;(2S,5R)-1-Boc-2,5-diMethylpiperazine hydrochloride;(2S,5R)-2,5-DiMethyl-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester;(2S,5R)-1-Boc-2,5-diMethylpiperazine/(2S,5R)-tert-butyl 2,5-diMethylpiperazine-1-carboxylate;(2S,5R)-2,5-Dimethyl-1-piperazinecarboxylic acid tert-butyl ester;(2|S|,5S|S|)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER | | CAS: | 548762-66-9 | | MF: | C11H22N2O2 | | MW: | 214.3 | | EINECS: | | Product Categories: | Amines;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators | | Mol File: | 548762-66-9.mol |
| (2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Chemical Properties |
| Boiling point | 280℃ | | density | 0.970 | | Fp | 123℃ | | storage temp. | 2-8°C(protect from light) | | pka | 8.55±0.60(Predicted) |
| (2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Usage And Synthesis |
| Uses | An intermediate used in the synthesis of a series of derivatives of the 4-fluorobenzyl dimethylpiperazine-indole class of p38α MAP kinase inhibitors with improved pharmacokinetic properties.
An intermediate used in the enantioselective synthesis of (-)-1-allyl-(2S,5R)-dimethylpiperazine (I), an important intermediate in the synthesis of δ-opioid receptor ligands. |
| (2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials |
| Raw materials | 1,4-Piperazinedicarboxylic acid, 2,5-dimethyl-, 4-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2R,5S)--->1-Piperazinecarboxylic acid, 2,5-dimethyl-, phenylmethyl ester, (2R,5S)--->Piperazine, 2,5-dimethyl-1-(2-propenyl)-, (2S,5R)- (9CI)-->Di-tert-butyl dicarbonate |
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