7-Ethylcamptothecin

7-Ethylcamptothecin
  • CAS No.:78287-27-1
Other grades of this product :
7-Ethylcamptothecin Basic information
Product Name:7-Ethylcamptothecin
Synonyms:IRINOTECAN EP IMPURITY F (7-ETHYL CAMPTOTHECIN);(S)-4,11-diethyl-4-hydroxy-1H;7-Ethylcamptothecin 78287-27-1;Irinotecan EP Impurity F;(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;SN 22;7-Ethylcamptotrecin
CAS:78287-27-1
MF:C22H20N2O4
MW:376.41
EINECS:
Product Categories:Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:78287-27-1.mol
7-Ethylcamptothecin Chemical Properties
Melting point 236-241°C
Boiling point 752.9±60.0 °C(Predicted)
density 1.43
storage temp. Sealed in dry,2-8°C
solubility Chloroform and Methanol Mixture (Slightly, Heated, Sonicated), DMSO (Slightly, H
pka11.24±0.20(Predicted)
form Solid
color Pale Yellow to Light Orange
InChIKeyMYQKIWCVEPUPIL-JOCHJYFZSA-N
CAS DataBase Reference78287-27-1(CAS DataBase Reference)
Safety Information
Risk Statements 23/34/35
Safety Statements 3/14-6-36/37/39
RIDADR 1544
HazardClass 6.1
PackingGroup III
HS Code 29349990
MSDS Information
7-Ethylcamptothecin Usage And Synthesis
Chemical PropertiesLight Pink Solid
UsesAn anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E.
UsesAn anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors.
Biological Activity7-Ethylcamptothecin is one of the camptothecin analogs. Camptothecin (CPT), a cytotoxic alkaloid isolated from camptothecin analogues, has strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models.
7-Ethylcamptothecin Preparation Products And Raw materials

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