Choline glycerophosphate

Choline glycerophosphate
  • CAS No.:28319-77-9
Other grades of this product :
Choline glycerophosphate Basic information
Product Name:Choline glycerophosphate
Synonyms:2-[[(2R)-2,3-dihydroxypropoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium;L-A-GLYCEROPHOSPHORYLCHOLINE FROM*EGG YOLK FREE FORM;L-A-GLYCEROPHOSPHORYLCHOLINE FROM SOYBEAN, FREE FORM;L-α-GLYCERYLPHOSPHORYLCHOLINE(GPC);,hydroxide,innersalt,(r)-;L-a-Glycerophosphorylcholine (anhydrous) (GPC);L-α-Glycerophosphorylcholine;GLYCERYLPHOSPHOCHOLINE
CAS:28319-77-9
MF:C8H20NO6P
MW:257.22
EINECS:248-962-2
Product Categories:GPC;Smart drug;Activity Other;Activity;Enzyme Substrates;pharmaceutical ingredients;28319-77-9
Mol File:28319-77-9.mol
Choline glycerophosphate Chemical Properties
Melting point 142.5-143°
alpha D25 -2.7° (c = 2.7 in water, pH 2.5); D25 -2.8° (c = 2.6 in water, pH 5.8)
Boiling point 480℃[at 101 325 Pa]
vapor pressure 0Pa at 25℃
Fp 11 °C
storage temp. -20°C
solubility DMSO (Slightly, Heated, Sonicated), Methanol (Sparingly), Water (Sparingly)
form solid
color White to Off-White
Water Solubility 1000g/L at 25℃
Stability:Very Hygroscopic
LogP-5.15 at 25℃
CAS DataBase Reference28319-77-9(CAS DataBase Reference)
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25
Safety Statements 16-36/37-45-24/25
RIDADR UN 1230 3/PG 2
WGK Germany 2
RTECS KH2775000
HS Code 29239000
MSDS Information
ProviderLanguage
Choline glycerophosphate English
SigmaAldrich English
Choline glycerophosphate Usage And Synthesis
DescriptionCholine alfoscerate is a nootropic reportedly effective in the treatment of age-associated memory impairment. In man, it decreased and prevented scopolamine-induced amnesia. In vitro studies suggest that choline alfoscerate acts indirectly on cholinergic transmission by elevating the synthesis of acetylcholine.
Chemical PropertiesWhite waxy solid
OriginatorSandoz; Italfarmaco (Italy)
Usessn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. sn-Glycero-3-phosphocholine is used as an Nootropic.
UsesL-α-Glycerophosphorylcholine has been used to rescue choline auxotrophy. It has also been used for the synthesis of glycerophospholipids.
DefinitionChEBI: A member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells.
Brand nameDelecit
General DescriptionL-α-Glycerophosphorylcholine is a phospholipid, which is a derivative of phosphatidylcholine.
Flammability and ExplosibilityNotclassified
Biochem/physiol ActionsIncreases inositol phosphate formation.
Choline glycerophosphate Preparation Products And Raw materials
Preparation Products1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE-->1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE-->1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

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