AURANTIO-OBTUSIN

AURANTIO-OBTUSIN
  • CAS No.:67979-25-3
Other grades of this product :
AURANTIO-OBTUSIN Basic information
Product Name:AURANTIO-OBTUSIN
Synonyms:1,3,7-Trihydroxy-2,8-diMethoxy-6-Methyl-9,10-anthracenedione;Aurantio-obtusifolin;AURANTIO-OBTUSIN;1,3,7-Trihydroxy-2,8-dimethoxy-6-methylanthracene-9,10-dione;URANTIO-OBTUSIN;Aurantioobtusin, 98%, from Catsia tora Linn;9,10-Anthracenedione, 1,3,7-trihydroxy-2,8-dimethoxy-6-methyl-;67979-25-3 AURANTIO-OBTUSIN
CAS:67979-25-3
MF:C17H14O7
MW:330.29
EINECS:
Product Categories:chemical reagent;pharmaceutical intermediate;Intermediates & Fine Chemicals;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Pharmaceuticals
Mol File:67979-25-3.mol
AURANTIO-OBTUSIN Chemical Properties
Melting point 265-266 °C
Boiling point 594.6±50.0 °C(Predicted)
density 1.510±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka6.32±0.20(Predicted)
Safety Information
Safety Statements 24/25
HS Code 29389090
MSDS Information
AURANTIO-OBTUSIN Usage And Synthesis
DescriptionAurantioobtusin is an anthraquinone originally isolated from Cassia seeds with diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro (IC50 = 13.6 μM). Aurantioobtusin (10 and 100 μM) activates the aryl hydrocarbon receptor (AhR) in a concentration-dependent manner. It inhibits rat platelet aggregation induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607), ADP, and collagen. Aurantioobtusin induces vasorelaxation in isolated precontracted rat mesenteric artery rings, an effect that is inhibited by the PI3K inhibitor LY290042 or inhibition of endothelial nitric oxide synthase (eNOS). It is larvicidal against A. gambiae mosquitoes (LD50 = 10 ppm).
UsesA compound found in herbal remedies, believed to have an effect on blood platelet aggregation and lower blood lipid count
DefinitionChEBI: A trihydroxyanthraquinone that is 1,3,7-trihydroxy-9,10-anthraquinone which is by methoxy groups at positions 2 and 8, and by a methyl group at position 6.
AURANTIO-OBTUSIN Preparation Products And Raw materials
Raw materials1,4-Naphthalenedione, 7-(acetyloxy)-5-hydroxy-6-methoxy--->1,4-Benzoquinone

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