Other grades of this product :
| Climbazole Chemical Properties |
| Melting point | 96-100°C | | Boiling point | 447.5±40.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | vapor pressure | 0.001Pa at 25℃ | | refractive index | 1.54 | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Insoluble in water | | pka | 5.66±0.22(Predicted) | | form | neat | | color | White to Almost white | | Water Solubility | 58mg/L at 25℃ | | BRN | 618020 | | InChIKey | OWEGWHBOCFMBLP-UHFFFAOYSA-N | | LogP | 3.83 at 25℃ | | CAS DataBase Reference | 38083-17-9(CAS DataBase Reference) |
| Hazard Codes | Xn,N | | Risk Statements | 22-50/53 | | Safety Statements | 60-61 | | RIDADR | UN 3077 | | WGK Germany | 3 | | RTECS | EL7085000 | | HS Code | 29332900 |
| Climbazole Usage And Synthesis |
| Risks to the environment | Climbazole (CBZ) is an emerging recalcitrant contaminant in wastewater, which has severe toxic effects on aquatic organisms. | | Description | (±)-Climbazole is an imidazole antifungal agent. It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = <0.06-1 μg/ml) and M. furfur (MICs = <0.06-0.5 μg/ml) in vitro. It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo. (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver. Formulations containing climbazole have been used in the treatment of dandruff. | | Chemical Properties | White Solid | | Uses | Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix.
s assay and did not induce micronuclei in human lymphocytes. | | Hazard | Moderately toxic by ingestion. Low toxicity by skin contact. | | Flammability and Explosibility | Nonflammable | | Side effects |
May cause localized irritation of the skin with symptoms including redness, rashes and itching.
|
| Climbazole Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye