BOLTON-HUNTER REAGENT
BOLTON-HUNTER REAGENT
  • CAS No.:34071-95-9
Other grades of this product :
BOLTON-HUNTER REAGENT Basic information
Product Name:BOLTON-HUNTER REAGENT
Synonyms:3-(P-HYDROXYPHENYL)PROPIONIC ACID*N-HYDR OXYSUCCINIM;3-(4-HYDROXYPHENYL)PROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER, TECH., 90%;3-(4-HYDROXYPHENYL)PROPIONIC ACID N-HYDR OXYSUCCINIMIDE ESTE;3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester, 99+%;3-(4-hydroxyphenyl)propionic acid N-hydroxysuccinimide est;N-[(4-Hydroxyhydrocinnamoyl)oxy]succinimide, N-Succinimidyl 3-(4-hydroxyphenyl)propionate, Bolton-Hunter reagent precursor, Rudinger reagent, SHPP;3-(4'-Hydroxyphenyl)propionic Acid N-Hydroxysuccinimide;Rudinger reagent, Bolton-Hunter reagent
CAS:34071-95-9
MF:C13H13NO5
MW:263.25
EINECS:251-818-1
Product Categories:Aromatic Propionic Acids;iodination
Mol File:34071-95-9.mol
BOLTON-HUNTER REAGENT Chemical Properties
Melting point 132-133 °C(lit.)
Boiling point 406.49°C (rough estimate)
density 1.2705 (rough estimate)
refractive index 1.5480 (estimate)
storage temp. -20°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (
form Solid
pka9.93±0.15(Predicted)
color White to Light Orange
Water Solubility Soluble in water.
BRN 1545011
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
10-21
HS Code 2928009090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
BOLTON-HUNTER REAGENT Usage And Synthesis
Chemical Propertieswhite to off-white powder
UsesBolton-Hunter Reagent is used for iodination of proteins that do not contain tyrosine residues, Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.
Uses3-(4-Hydroxyphenyl)propionic acid?N-hydroxysuccinimide ester can be used to prepare 125I-labeled reagents, which are used in binding assay studies of proteins and peptides.
BOLTON-HUNTER REAGENT Preparation Products And Raw materials
Raw materials4-Hydroxycinnamic acid-->N-Hydroxysuccinimide-->3-(4-Hydroxyphenyl)propionic acid

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