TMPYP

TMPYP
  • CAS No.:36951-72-1
Other grades of this product :
TMPYP Basic information
Product Name:TMPYP
Synonyms:5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphine tetratosylate;TMPY;TMPYP;5,10,15,20-TETRAKIS-(N-METHYL-4-PYRIDYL)-21,23H-PORPHYRIN TETRATOSYLATE;5,10,15,20-TETRAKIS (1-METHYL-4-PYRIDINIO) PORPHINE TETRA (P-TOLUENESULFONATE);5,10,15,20-TETRAKIS(1-METHYL-4-PYRIDINIO)-PORPHYRIN TETRA(P-TOLUENESULFONATE);5,10,15,20-TETRAKIS(1-METHYL-4-PYRIDINIO)PORPHYRIN TETRA(TOLUENE-4-SULFONATE);5,10,15,20-TETRAKIS(1-METHYL-4-PYRIDYL)-21H,23H-PORPHINE, TETRA-P-TOSYLATE SALT
CAS:36951-72-1
MF:C72H66N8O12S4
MW:1363.6
EINECS:
Product Categories:Porphyrins;Synthetic Porphyrins;Analytical Chemistry;Biochemistry;Chelating Reagents;Ligands for Pharmaceutical Research;Magnetic Resonance Imaging (Chelating Reagents);Porphines;Pyridinium Compounds
Mol File:36951-72-1.mol
TMPYP Chemical Properties
Melting point >300℃
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility water: soluble50MM(lit.)
form Purple solid
color Dark red to Dark purple to Dark blue
BRN 6049195
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37
WGK Germany 3
3-8-10
MSDS Information
ProviderLanguage
SigmaAldrich English
TMPYP Usage And Synthesis
UsesTMPyP4 is a potent inhibitor of telomerase activity.
DefinitionChEBI: An organosulfonate salt that is the tetrakis(p-toluenesulfonate) salt of meso-tetrakis(N-methyl-4-pyridyl)porphine.
General Description5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p toluenesulfonate) (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent 1O2 luminescence signals on incubation with the fungus, Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer.
TMPYP Preparation Products And Raw materials
Preparation Products5,10,15,20-TETRAKIS-(N-METHYL-4-PYRIDYL)-21,23H-PORPHYRIN TETRACHLORIDE

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