SITS

SITS
  • CAS No.:51023-76-8
Other grades of this product :
SITS Basic information
Product Name:SITS
Synonyms:disodium 5-acetamido-2-[2-(4-isothiocyanato-2-sulphonatophenyl)vinyl]benzenesulphonate;4-ACETAMIDO-4'-ISOTHIOCYANATO-STILBENE-2 ,2'-DISULF.ACID-NA;4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2- 2'-DISULFO;acetamidoisothiocyanato-stilbenedisulfonic acid disodium;4-Acetamido-4μ-isothiocyanato-2,2μ-stilbenedisulfonic acid hydrate disodium salt;SITS, Disodium 4-acetamido-4μ-isothiocyanato-stilben-2,2μ-disulfonate;4-Acetylamino-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium salt;5-(Acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid disodium salt
CAS:51023-76-8
MF:C17H12N2Na2O7S3
MW:498.46
EINECS:256-919-4
Product Categories:Aromatics;Sulfur & Selenium Compounds;Fluorescent Labels & Indicators;marker;Stilbene
Mol File:51023-76-8.mol
SITS Chemical Properties
Melting point >300°C (dec.)
storage temp. -20°C
solubility Soluble in water, methanol, dimethyl sulfoxide
form powder
color Yellow or tan-yellow
λmax336 nm
BRN 9177451
Stability:Temperature sensitive - recommended storage at -20oC
Biological ApplicationsChloride channel blockers; anion transport inhibitors; treating cancer,glaucoma,heart diseases,viral diseases
CAS DataBase Reference51023-76-8(CAS DataBase Reference)
EPA Substance Registry SystemBenzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, disodium salt (51023-76-8)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38-42
Safety Statements 22-26-36/37
WGK Germany 3
8-10-21
HS Code 2930909899
MSDS Information
ProviderLanguage
SigmaAldrich English
SITS Usage And Synthesis
Chemical PropertiesLight Yellow Solid
UsesA fluorescent label for the specific and reversible labelling of the outer components of the plasma membrane. The reagent reacts with a fixed number of sites on the surface of cells concerned with anion permeation; does not pass through the osmotic barrier of the membrane; reacts under physiological conditions of temperature, pH and tonicity; and is detectable in small amounts. SEE ALSO NOTES FOR DIDS (CAT#D460600). Fluorescence: max. Abs. l = 336nm, max. Em. l = 436 nm.
UsesFluorescent marker for membranes; inhibits anion permeability of membranes. Also inactivates Na,K-ATPase, by covalent modification of a specific Lys residue.
SITS Preparation Products And Raw materials

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