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| PHTHALAMIC ACID Basic information |
| PHTHALAMIC ACID Chemical Properties |
| Melting point | 140-143 °C(lit.) | | Boiling point | 394.2±25.0 °C(Predicted) | | density | 1.368 | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 3.75±0.10(Predicted) | | color | White to Off-White | | BRN | 1868205 | | CAS DataBase Reference | 88-97-1(CAS DataBase Reference) | | EPA Substance Registry System | Benzoic acid, 2-(aminocarbonyl)- (88-97-1) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | TSCA | Yes | | HazardClass | IRRITANT | | HS Code | 2924297099 |
| PHTHALAMIC ACID Usage And Synthesis |
| Uses | Phthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity. | | Uses | Phthalamic acid may be used to synthesize anthranilic acid via reaction with sodium hypochlorite. | | General Description | Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (kobs) as 5.1×10-5sec-1 at pH 1.3-1.8 and 35°C. It undergoes hydrolysis about 105 times faster than benzamide. |
| PHTHALAMIC ACID Preparation Products And Raw materials |
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