(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide

(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide
  • CAS No.:95713-52-3

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Basic information
Product Name:(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide
Synonyms:1-FLUORO-2,4-DINITROPHENYL-5-L-ALANINE AMIDE;Nα-(2,4-Dinitro-5-fluorophenyl)-L-alanine amide≥ 98% (HPLC);NALPHA-(5-FLUORO-2,4-DINITROPHENYL)-L-ALANINAMIDE;N-ALPHA-(2,4-DINITRO-5-FLUOROPHENYL)-L-ALANINAMIDE;N-ALPHA-(2,4-DINITRO-5-FLUOROPHENYL)-L-ALANINE AMIDE;(2,4-Dinitro-5-fluorophenyl) L-Alaninamide;Marfey's Reagent, 99%, for chiral derivatization;Nalpha-(5-Fluoro-2,4-dinitrophenyl)-L-alaninamide [HPLC Labeling Reagent for e.e. Determination]
CAS:95713-52-3
MF:C9H9FN4O5
MW:272.19
EINECS:
Product Categories:proteinmod;Amino Acids & Derivatives;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Group Labeling Reagents for HPLC;Analytical Chemistry;e.e. Determination (HPLC Labeling Reagents);Enantiomer Excess & Absolute Configuration Determination;HPLC Labeling Reagents;UV Detection (HPLC Labeling Reagents)
Mol File:95713-52-3.mol
(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Chemical Properties
Melting point 229 °C
Boiling point 544.5±50.0 °C(Predicted)
density 1.592±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility acetone: 10 mg/mL, clear, yellow
form powder
pka15.61±0.50(Predicted)
color yellow to orange
optical activity[α]20/D +56±2°, c = 1% in acetone
BRN 6820069
InChIKeyNEPLBHLFDJOJGP-BYPYZUCNSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29242990
MSDS Information
ProviderLanguage
SigmaAldrich English
(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Usage And Synthesis
Chemical PropertiesLight yellow to yellow crystal or powder
UsesFDAA was used as derivatizing reagent, in a study performed to understand unusual amino acids using reversed phase high performance liquid chromatography-electrospray ionization mass spectrometry (RPHPLC-ESI-MS).
Uses(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide can be used for chiral amino acid analysis.
UsesN-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide is suitable for use for the derivatization of amino acids. glutamate and analine present in cell wall. Derivatized?D- and?L-amino acids can be resolved and quantitated by HPLC.
General DescriptionNα-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent (CDA), has high enantioselectivity but low sensitivity as compared to other CDAs. It is generally used to assign the stereochemistry of amino acids in trace amounts.
Biochem/physiol ActionsN-α-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide (FDAA) is a chiral derivatizing agent and is used routinely to improve the detection of underivatized amino acids in high performance liquid chromatography. Its usage is effective in separating stereoisomer.
(S)-2-(5-fluoro-2,4-dinitrophenylaMino)propanaMide Preparation Products And Raw materials

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