| CP 96345 Basic information |
| Product Name: | CP 96345 |
| Synonyms: | (2S,3S)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine;CP 96345;(2S)-2β-(Diphenylmethyl)-N-(2-methoxybenzyl)-1-azabicyclo[2.2.2]octan-3β-amine;(2S)-2β-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3β-amine;(2S)-2β-Diphenylmethyl-3β-(2-methoxybenzylamino)-1-azabicyclo[2.2.2]octane;(2S)-N-(2-Methoxybenzyl)-2β-benzhydryl-1-azabicyclo[2.2.2]octane-3β-amine;CP-96345-1;(2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine |
| CAS: | 132746-60-2 |
| MF: | C28H32N2O |
| MW: | 412.57 |
| EINECS: | |
| Product Categories: | Aromatics;Chiral Reagents;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pfizer Compounds;Pharmaceuticals |
| Mol File: | 132746-60-2.mol |
| CP 96345 Chemical Properties |
| storage temp. | room temp |
| solubility | DMSO: soluble24mg/mL |
| form | white powder |
| Safety Information |
| Hazard Codes | Xn,N |
| Risk Statements | 22-36/37/38-50/53 |
| Safety Statements | 26-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| MSDS Information |
| CP 96345 Usage And Synthesis |
| Uses | CP 96345 is a potent and selective non-peptide NK1 receptor antagonist. CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo. |
| Uses | CP 96345 is a potent and selective non-peptide NK1 receptor antagonist (1,2,3). CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo. |
| Biological Activity | Potent and selective non-peptide NK 1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo . |
| Biochem/physiol Actions | CP-96345 is a selective NK1 antagonist. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors. |
| CP 96345 Preparation Products And Raw materials |
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