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| 3,7-DIMETHYL-1-PROPARGYLXANTHINE Basic information |
| Product Name: | 3,7-DIMETHYL-1-PROPARGYLXANTHINE | | Synonyms: | DMPX;3,7-DIMETHYL-1-PROPARGYLXANTHINE;3,7-DIMETHYL-1-(2-PROPYNYL)XANTHINE;3,7-DIMETHYL-1-PROPARGYLXANTHINE (DMPX) ADENOSINE ANTAGONIST;DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine;3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX;1-(2-Propynyl)-3,7-dimethyl-7H-purine-2,6(1H,3H)-dione;1-(2-Propynyl)-3,7-dimethylxanthine | | CAS: | 14114-46-6 | | MF: | C10H10N4O2 | | MW: | 218.21 | | EINECS: | | Product Categories: | All Inhibitors;Inhibitors;Heterocycles | | Mol File: | 14114-46-6.mol |
| 3,7-DIMETHYL-1-PROPARGYLXANTHINE Chemical Properties |
| Melting point | 204-205°C | | storage temp. | -20°C Freezer | | solubility | DMSO: ≥15 mg/mL | | form | solid | | color | white | | CAS DataBase Reference | 14114-46-6 |
| 3,7-DIMETHYL-1-PROPARGYLXANTHINE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 4 uM | | Uses | A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM. | | Uses | 3,7-Dimethyl-1-propargylxanthine (DMPX) has been used as an A2 -adenosine receptor (AR) antagonist:- to study its effects on potential modulation of motor output elicited by epidural spinal stimulation (ESS)
- to study the role of A2a?receptor in elevating cyclic adenosine monophosphate (cAMP) levels
- to study its effects on the cell viability of human gastric cancer cell line
| | Biochem/physiol Actions | 3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A2-selective adenosine receptor (AR) antagonist. |
| 3,7-DIMETHYL-1-PROPARGYLXANTHINE Preparation Products And Raw materials |
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