1,1-Cyclohexanediacetic acid mono amide

1,1-Cyclohexanediacetic acid mono amide
  • CAS No.:99189-60-3
Other grades of this product :
1,1-Cyclohexanediacetic acid mono amide Basic information
Product Name:1,1-Cyclohexanediacetic acid mono amide
Synonyms:1,1-Cychexanediaceticacidmonoamide;1,1-CYCLOHESANEDIACETIS ACID MONOAMIDE;CALM;CALM1;CALML2;Calmodulin1, His tagged human;CAMI;DD132
CAS:99189-60-3
MF:C10H17NO3
MW:199.25
EINECS:619-402-8
Product Categories:INTERMEDIATESOFGABAPENTIN;Organic acids;Pharmaceutical intermediates
Mol File:99189-60-3.mol
1,1-Cyclohexanediacetic acid mono amide Chemical Properties
Melting point 141-146 °C (lit.)
Boiling point 443.6±18.0 °C(Predicted)
density 1.135±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka4.72±0.10(Predicted)
color White to Off-White
LogP0.73 at 22℃ and pH3
CAS DataBase Reference99189-60-3(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 61
Safety Statements 22-24/25-45-53
WGK Germany 3
HS Code 29242990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
1,1-Cyclohexanediacetic acid mono amide Usage And Synthesis
Chemical PropertiesWhite powder
Uses1,1-Cyclohexanediacetic acid monoamide is an impurity of Gabapentin (G117250), an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier.?Gabapentin is used as an anticonvulsant.
General Description1,1-Cyclohexanediacetic acid monoamide, also known as gabapentin amide, has neurological properties. It is an important intermediate formed during the synthesis of a potential antiepileptic drug, gabapentin.
1,1-Cyclohexanediacetic acid mono amide Preparation Products And Raw materials
Raw materials1,1-Cyclohexanediacetic acid-->3,3-Pentamethylene glutarimide-->1,1-Cyclohexane diacetic anhydride
Preparation ProductsGabapentin-lactam

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