POLY-L-HISTIDINE HYDROCHLORIDE MW

CAS No.：26062-48-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
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POLY-L-HISTIDINE HYDROCHLORIDE MW Basic information

Product Name:	POLY-L-HISTIDINE HYDROCHLORIDE MW
Synonyms:	polyhistidine;POLY-L-HISTIDINE HYDROCHLORIDE MW;POLY-L-HISTIDINE MOL WT 5000-15000;POLY-L-HISTIDINE, HYDROCHLORIDE*MW 15,00 0-50,000;poly-L-HistidineMW5000-15000;poly-L-histidine chloride;Poly-L-histidine mol wt 5,000-25,000
CAS:	26062-48-6
MF:	C6H9N3O2
MW:	155.16
EINECS:
Product Categories:	Amino Acids;Homopolymers;Polyamino Acids
Mol File:	26062-48-6.mol

POLY-L-HISTIDINE HYDROCHLORIDE MW Chemical Properties

storage temp.

-20°C

Safety Information

WGK Germany

MSDS Information

POLY-L-HISTIDINE HYDROCHLORIDE MW Usage And Synthesis

Uses	Poly-L-histidine has been used: as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs) as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane in screening its anti-prion activity in cell based and in vivo anti-prion assay
General Description	Poly-L-histidine is an amphoteric compound. The imidazole ring in its structure enables protonation?deprotonation.
Biochem/physiol Actions	Poly-L-histidine (Phis) copolymers are biocompatible, pH responsive and are less toxic. It exhibits endolysosomal escape funcationality. The copolymer of Phis with poly(ethylene glycol)?poly(d,l-lactide) (PEG-PLA) is effective in delivering doxorubicin. pH sensitive poly(l-histidine) copolymer micelles have application in delivering anticancer drugs in acidic microenvironment.

POLY-L-HISTIDINE HYDROCHLORIDE MW Preparation Products And Raw materials

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