2-(2-HYDROXYPHENYL)-1H-BENZIMIDAZOLE

CAS No.：2963-66-8

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-(2-HYDROXYPHENYL)-1H-BENZIMIDAZOLE Basic information

Product Name:	2-(2-HYDROXYPHENYL)-1H-BENZIMIDAZOLE
Synonyms:	2-(2-Hydroxyphenyl)-1H-benziMidazole 95%;2-(2-HYDROXYMETHYL)-1H-BENZIMIDAZOLE;2-(1H-Benzimidazole-2-yl)phenol, 2-(1H-Benzimidazole-Z-yl)phenol, 2-(1H-Benzoimidazol-2-yl)-phenol;o-(1H-Benzimidazol-2-yl)phenol;2-(2-Hydroxyphenyl)benzimidazole;O-hydroxyphenylbenzimidazole;Phenol, O-2-benzimidazolyl-;2-(2-benzimidazolyl)phenol
CAS:	2963-66-8
MF:	C13H10N2O
MW:	210.23
EINECS:
Product Categories:	Benzimidazoles;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Fluorescent
Mol File:	2963-66-8.mol

2-(2-HYDROXYPHENYL)-1H-BENZIMIDAZOLE Chemical Properties

Melting point	239-243 °C
Boiling point	444.2±47.0 °C(Predicted)
density	1.323±0.06 g/cm3(Predicted)
solubility	Solubility Insoluble in water; soluble in ethanol
form	crystals
pka	9.23(at 25℃)
color	White to tan
PH Range	Non0 uorescence (<9.9) to blue-violet 0 uorescence (9.9)
λmax	245nm, 300nm
Major Application	Optical devices, photography, plastic scintillation applications, fungicide, antiviral agent, antiinflammatory agent, antibacterial agent
EPA Substance Registry System	Phenol, 2-(1H-benzimidazol-2-yl)- (2963-66-8)

Safety Information

Hazard Codes	Xn
Risk Statements	22-37/38-41
Safety Statements	26-36/37/39
WGK Germany	3

MSDS Information

2-(2-HYDROXYPHENYL)-1H-BENZIMIDAZOLE Usage And Synthesis

Uses	2-(2-Hydroxyphenyl)-1H-benzimidazole is a chemical reagent used in pharmaceutical syntheses. Used in the synthesis of selective inhibitors of PI3Kα against human tumor cell lines.

2-(2-HYDROXYPHENYL)-1H-BENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

2-(1-(2-hydroxybenzyl)-1H-benzo[d]imidazol-2-yl)phenol-->N,N'-DISALICYLAL-1,2-PHENYLENEDIAMINE-->Salicylaldehyde-->o-Phenylenediamine

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