5-Bromoindole
5-Bromoindole
  • CAS No.:10075-50-0
Other grades of this product :
5-Bromoindole Basic information
Product Name:5-Bromoindole
Synonyms:5-BROMOINDOLE;5-BI;5-BROMO-1H-INDOLE;5-Bromindole;5-bromonindole;5-Bromide indole;Bromoindole-99%;5-Bromoindole99%
CAS:10075-50-0
MF:C8H6BrN
MW:196.04
EINECS:233-208-7
Product Categories:Halogenated Heterocycles;Heterocyclic Building Blocks;Organohalides;Simple Indoles;Pyrroles & Indoles;IndolesBuilding Blocks;Indole/indoline/oxindole;Indoles and derivatives;IndoleDerivative;Halides;Indoles;Pharmaceutical Intermediates;Indole Derivatives;Heterocycle-Indole series;blocks;Bromides;IndolesOxindoles;Pyrroles & Indoles;Indole;bc0001
Mol File:10075-50-0.mol
5-Bromoindole Chemical Properties
Melting point 90-92 °C (lit.)
Boiling point 228.5°C (rough estimate)
density 1.5466 (rough estimate)
refractive index 1.6550 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 126mg/l (calculated)
form Powder or Chunks
pka16.04±0.30(Predicted)
color White to light brown
BRN 112877
InChIKeyVXWVFZFZYXOBTA-UHFFFAOYSA-N
CAS DataBase Reference10075-50-0(CAS DataBase Reference)
EPA Substance Registry System1H-Indole, 5-bromo- (10075-50-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25-37/39
WGK Germany 3
Hazard Note Irritant
HS Code 29339990
MSDS Information
ProviderLanguage
5-Bromo-1H-indole English
ACROS English
SigmaAldrich English
ALFA English
5-Bromoindole Usage And Synthesis
Chemical Propertieswhite to light brown powder or chunks
UsesA potential inhibitor of GSK-3
Purification MethodsPurify it by steam distillation from a faintly alkaline solution. Cool the aqueous distillate, collect the solid, dry it in a vacuum desiccator over P2O5 and recrystallise it from aqueous EtOH (35% EtOH) or pet ether/Et2O. UV in MeOH has at 279, 287 and 296nm (log 3.70, 3.69 and 3.53). The picrate has m 137-138o(dec) (from max Et2O/pet ether). [UV: Thesing et al. Chem Ber 95 2205 1962, UV and NMR: Lallemand & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 20/7 V 36.]

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