Ketotifen Fumarate

Overview

Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis,or the itchy red eyes caused by allergies. In its oral form, it is used to preventasthma attacks.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Endocrinology and Metabolic Disease | Histamine Receptor

Product Information

• Catalog No.: B0046-463927
• CAS No.: 34580-14-8
• Molecular Formula: C19H19NOS.C4H4O4
• Molecular Weight: 425.5
• Purity: >98%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
• Solubility: In Vitro : DMSO : ≥ 100 mg/mL(235.02 mM) H2O : 16.67 mg/mL(39.18 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:PBS Solubility: 37.5 mg/mL (88.13 mM); Clear solution; Need ultrasonic 2.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (5.88 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.5 mg/mL (5.88 mM); Clear solution

Source

Original product source