Dapagliflozin

Dapagliflozin
  • CAS No.:461432-26-8
  • Grade:>98%
  • Formula:C21H25ClO6
  • M.W.:408.87
  • Solvent:Soluble in DMSO, Methanol

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Dapagliflozin is a synthetic C-glucoside compound classified as a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor. Supplied as a stable, crystalline powder, it demonstrates high solubility in organic solvents and notable resistance to enzymatic hydrolysis. By inhibiting SGLT2 in renal proximal tubules, dapagliflozin modulates glucose reabsorption and fosters glycosuric effects, making it a valuable tool in metabolic and renal research. Frequently utilized in studies of glucose homeostasis, cellular transport mechanisms, and metabolic pathway modulation, dapagliflozin supports advanced biochemical investigations.

Application

Products > Drug Discovery > Impurities > Anti-Diabetic > Dapagliflozin and Impurities | Products > Drug Discovery > Inhibitor

Product Information

  • Catalog No.: B0084-069214
  • CAS No.: 461432-26-8
  • Molecular Formula: C21H25ClO6
  • Molecular Weight: 408.87
  • Purity: >98%
  • Storage: Store at -20°C
  • Solubility: Soluble in DMSO, Methanol

Source

Original product source


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