Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Products > Drug Discovery > Impurities > Anti-Neoplastic > Afatinib and Impurities | Products > Drug Discovery > Inhibitor
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