Dolutegravir

Overview

Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI).

Application

Products > Drug Discovery > Impurities > Anti-Hiv > Dolutegravir and Impurities | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B0084-438457
• CAS No.: 1051375-16-6
• Molecular Formula: C20H19F2N3O5
• Molecular Weight: 419.38
• Purity: ≥98%
• Storage: Store at 2-8 °C
• Solubility: Soluble in DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated)

Source

Original product source