Tenofovir alafenamide hemifumarate

Overview

Tenofovir alafenamide hemifumarate, also known as Tenofovir alafenamide fumarate (2:1), is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevents HIV from multiplying and can reduce the amount of HIV in the body.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Infection | NRTIs

Product Information

• Catalog No.: B0084-470850
• CAS No.: 1392275-56-7
• Molecular Formula: C46H62N12O14P2
• Molecular Weight: 1069.02
• Purity: > 98%
• Storage: Powder : -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
• Solubility: In Vitro : DMSO: 50 mg/mL H2O: 20 mg/mL In Vivo: 1.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (4.68 mM) 2.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline) Solubility: 2.5 mg/mL (4.68 mM) 3.Add each solvent one by one: 10% DMSO >> 90% corn oil saline Solubility: ≥ 2.5 mg/mL (4.68 mM)

Source

Original product source