Harpagoside, isolated from the Harpagophytum procumbens (Devil's Claw) root or Crophularia ningpoensis Hemsl (Figwort), inhibited lipopolysaccharide-induced mRNA levels. Harpagoside also inhibited protein expression of cyclooxygenase-2 and inducible nitric oxide in HepG2 cells, which involves suppression of NF-kappaB activation, thereby inhibiting downstream inflammation and subsequent pain events. Source summary: Order Harpagoside, a valuable iridoid glycoside, supplied for advanced biochemical research and natural product synthesis—buy now for reliable quality.
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