Tenofovir Disoproxil Fumarate

Tenofovir Disoproxil Fumarate
  • CAS No.:202138-50-9
  • Grade:98%
  • Formula:C19H30N5O10P.C4H4O4
  • M.W.:635.51
  • Solvent:In Vitro : DMSO : ≥ 50 mg/mL (78.68 mM) H2O : 16.67 mg/mL (26.23 mM; Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 2.Add each solvent one by one: 10% DMSO >>

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Infection | HIV

Product Information

  • Catalog No.: B2692-062397
  • CAS No.: 202138-50-9
  • Molecular Formula: C19H30N5O10P.C4H4O4
  • Molecular Weight: 635.51
  • Purity: 98%
  • Storage: 2 - 8°C
  • Solubility: In Vitro : DMSO : ≥ 50 mg/mL (78.68 mM) H2O : 16.67 mg/mL (26.23 mM; Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 2.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 3.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline) Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution

Source

Original product source


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