Tenofovir Disoproxil Fumarate

Overview

Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Infection | HIV

Product Information

• Catalog No.: B2692-062397
• CAS No.: 202138-50-9
• Molecular Formula: C19H30N5O10P.C4H4O4
• Molecular Weight: 635.51
• Purity: 98%
• Storage: 2 - 8°C
• Solubility: In Vitro : DMSO : ≥ 50 mg/mL (78.68 mM) H2O : 16.67 mg/mL (26.23 mM; Need ultrasonic and warming) In Vivo: 1.Add each solvent one by one: 10% DMSO >> 90% corn oil Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 2.Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution 3.Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline) Solubility: ≥ 2.5 mg/mL (3.93 mM); Clear solution

Source

Original product source