Oclacitinib monomaleate

Overview

Oclacitinib, also called as PF-03394197, is a novel inhibitor of JAK family members (IC50 = 10 - 99 nM) and JAK1-dependent cytokines involved in allergy, inflammation, and pruritus (IC50 = 36 - 249 nM), without affecting a panel of 38 non-JAK kinases. It could reduce pruritus and associated inflammatory skin lesions in dogs with AD.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Inflammation / Immunology | JAK

Product Information

• Catalog No.: B2693-008142
• CAS No.: 1640292-55-2
• Molecular Formula: C15H23N5O2S.C4H4O4
• Molecular Weight: 453.51
• Purity: ≥95%
• Storage: Store at -20°C under inert atmosphere
• Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Sonicated)

Source

Original product source