PF-07321332

Overview

PF-07321332 is an orally available SARS-CoV 3C-like protease (3CLPRO) inhibitor. 3C-like protease (3CLPRO) is the main protease found in coronaviruses, which cleaves the coronavirus polyprotein at eleven conserved sites. PF-07321332 has demonstrated oral activity in a mouse-adapted SARS-CoV-2 model and has achieved oral plasma concentrations exceeding the in vitro antiviral cell potency in a phase I clinical trial in healthy human participants.

Application

Products > Drug Discovery > Inhibitor > SARS-CoV-2 Inhibitors | Products > Drug Discovery > Inhibitor | Infection

Product Information

• Catalog No.: B2693-074195
• CAS No.: 2628280-40-8
• Molecular Formula: C23H32F3N5O4
• Molecular Weight: 499.53
• Purity: 98%
• Storage: -20°C
• Solubility: In vitro : 10 mM in DMSO

Source

Original product source