TC-S 7001

Overview

TC-S 7001 is a potent and highly selective ROCK inhibitor. Its IC50 values are 0.6 and 1.1 nM for ROCK1 and ROCK2, respectively. It exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. It reduces blood pressure in normotensive and hypertensive rats.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | ROCK

Product Information

• Catalog No.: B2693-430574
• CAS No.: 867017-68-3
• Molecular Formula: C18H13ClF2N6O
• Molecular Weight: 402.79
• Purity: >98 %
• Storage: -20°C Freezer
• Solubility: 10 mM in DMSO

Source

Original product source