Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib irreversibly binds to and inhibits the 20S catalytic core subunit of the proteasome by covalently modifying its active site threonine residues.
Products > Drug Discovery > Impurities > Anti-Neoplastic > Marizomib and Impurities | Products > Drug Discovery > Inhibitor
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