PF-04418948

Overview

PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cardiovascular and blood system | Prostaglandin Receptor

Product Information

• Catalog No.: B2693-470809
• CAS No.: 1078166-57-0
• Molecular Formula: C23H20FNO5
• Molecular Weight: 409.41
• Purity: 98%
• Storage: 3 years -20°C powder; 6 months -80°C in solvent
• Solubility: DMSO: 81mg/mL(197.84mM); Water: <1mg/mL(<1mM); Ethanol: <1mg/mL(<1mM)

Source

Original product source